How To Prescribe

Below are the steps you and your patient’s parents take to activate the treatment.

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First, complete the required order information.

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You can submit the order via our portal:

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When ordering, include instructions for play1

  • EndeavorRx is ordered just like a medication-with a specific dose.
  • We recommend ordering EndeavorRx for approximately 25 minutes a day, 5 days a week, for at least 4 consecutive weeks.
  • EndeavorRx demonstrates incremental efficacy with two months of treatment, so order with refills.

1. For more information, see Instructions for Use.

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Next, parents enroll, pay, and activate.

Parents can enroll online with a phone in a matter of minutes.

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Akili will validate and process the order submitted.

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Parent receives an email with a link to pay for treatment.

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Once payment is complete a follow up email is sent with a unique activation code.

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Parent downloads the app and activates treatment using the code.

Child can now start playing!

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Download the app

Try our free demo


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Parents should also pair treatment with our free companion app that tracks their child’s in-game progress.

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Then, guide your patient to make progress.

Follow up

Follow up both during & after treatment to discuss progress and next steps. Empower parents by learning more about our tips for success.



EndeavorRx demonstrates incremental efficacy with two months of treatment, so prescribe with refills.

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Cost for EndeavorRx

The current cost for EndeavorRx is $99 for a 30 day prescription. EndeavorRx is also FSA/HSA eligible. For questions, please contact [email protected].

We’re here to support you.


Indications, Safety and Cautions

EndeavorRx is a digital therapeutic indicated to improve attention function as measured by computer-based testing in children ages 8-17 years old with primarily inattentive or combined-type ADHD, who have a demonstrated attention issue. Patients who engage with EndeavorRx demonstrate improvements in a digitally assessed measure, Test of Variables of Attention (TOVA®), of sustained and selective attention and may not display benefits in typical behavioral symptoms, such as hyperactivity. EndeavorRx should be considered for use as part of a therapeutic program that may include clinician-directed therapy, medication, and/or educational programs, which further address symptoms of the disorder.

No serious adverse events were reported. Of 342 participants who received AKL-T01 in the two clinical trials supporting EndeavorRx authorization for age ranges 8-17, 17 participants (4.97%) experienced treatment-related adverse events (TE-ADE) (possible, probable, likely). TE-ADEs reported at greater than 1% across the studies include: frustration tolerance decreased (2.34%) and headache (1.17%). Other adverse events occurred less than 1% and included dizziness, emotional disorder, nausea, and aggression. All adverse events were transient and no events led to device discontinuation. Across other studies in children and adolescents with ADHD, rates of adverse events were similarly low (<10%) and no Serious Adverse Events have been reported. All reported adverse events across all clinical trials resolved at the end of treatment. Users should consider the totality of evidence presented along with their health care provider when considering incorporating AKL-T01 into their treatment plan.

Rx only: Federal law restricts this device to sale by or on the order of a licensed health care provider. EndeavorRx should only be used by the patient for whom the prescription was written. For medical questions, please contact your child’s healthcare provider. If you are experiencing a medical emergency, please dial 911. EndeavorRx is not intended to be used as a stand-alone therapeutic and is not a substitution for your child’s medication.

If your child experiences frustration, emotional reaction, dizziness, nausea, headache, eye-strain, or joint pain while playing EndeavorRx pause the treatment. If the problem persists contact your child’s healthcare provider. If your child experiences a seizure stop the treatment and contact your child’s healthcare provider.

EndeavorRx may not be appropriate for patients with photo-sensitive epilepsy, color blindness, or physical limitations that restrict use of a mobile device; parents should consult with their child’s healthcare provider.

Please follow all of your mobile device manufacturer’s instructions for the safe operation of your mobile device. For example, this may include appropriate volume settings, proper battery charging, not operating the device if damaged, and proper device disposal. Contact your mobile device manufacturer for any questions or concerns that pertain to your device.