How to Prescribe
A new clinically-validated, nonpharmacological therapeutic option for ADHD is now in your toolbox.
EndeavorRx is indicated for children ages 8-12 with primarily inattentive or combined-type ADHD, and should be considered as part of a therapeutic program that can work alongside other treatments.
When identifying suitable patients, it’s important to discuss the required time commitment (typically ~25 minutes a day, 5 days a week over initially at least 4 consecutive weeks, or as prescribed) and whether that seems feasible for a family at a particular time given other factors like school.
HCPs are advised to use our indications for use and characteristics of our trial participants as a benchmark to assess the types of patients who may derive benefit from EndeavorRx treatment.
The following document will help caregivers
determine if EndeavorRx is right for their child.
Using EndeavorRx in your practice
How do I get started?
Prescriptions can be sent to Phil pharmacy through your EHR found as PhilRx (Columbus, Ohio). If you cannot send prescriptions to Phil through EHR, you can call them directly at 855-977-0975 (Press 1) to provide the prescription over the phone or to obtain a form to fax to 888.975.0603.
To minimize callbacks, please include:
Diagnosis / Primary ICD-10 code
Instructions to play EndeavorRx per the Instructions For Use (IFU)* or other frequency of time per day, days per week, number of weeks, and length of break (if any)
Number of refills – *IFU Recommendation: EndeavorRx is recommended to be used for approximately 25 minutes a day, 5 days a week, over initially at least 4 consecutive weeks, or as recommended by a child’s health care provider
Watch: How to Prescribe EndeavorRx
Watch this simple video to learn how to prescribe
Authorization & activation
Once EndeavorRx treatment has been prescribed for your patient, the caregiver will receive a text message from Phil pharmacy with instructions on next steps.
Meanwhile, prescribers should submit prior authorizations to CoverMyMeds®. Phil pharmacy will initiate the prior authorization and send a key.
Once payment is processed, caregivers will receive an activation code via text and email, and download the EndeavorRx app from the App Store® or on Google Play™.
Cost & insurance coverage
A prescription for EndeavorRx costs no more than $99.
EndeavorRx may be covered by your patient’s health insurance and we’re actively working to improve options. If your patient’s health insurance doesn’t cover EndeavorRx, the cost is $99. If their insurance does cover EndeavorRx, it could cost even less.
What happens next?
HCPs should follow up with patients during and after treatment cycles to discuss results and next steps, same as you would after issuing a drug prescription. You can also refer caregivers to our Treatment Tips resource when getting started, or if their child is having difficulties committing to the treatment.
Subsequent refills will be billed and dispensed by Phil pharmacy. If your patient’s prescription is set to auto-refill, they should be contacted by Phil pharmacy, which will provide details regarding how to activate their next cycle. For more info about refilling prescriptions, caregivers can contact Phil directly by calling 855-977-0975 (Press 3) or visit phil.us/contact.
Check‑in daily with EndeavorRx Insight®
Before their child begins playing, parents can download our free EndeavorRx Insight companion app. It connects directly to their child’s treatment profile, so they can see a daily snapshot of their in‑game progress — including mission completion progress and perceived effort levels calculated based on in‑game interactions.
Consult our FAQ
If you have any additional questions, you can visit our FAQ page.
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Indications, Safety and Cautions
EndeavorRx is a digital therapeutic indicated to improve attention function as measured by computer-based testing in children ages 8-12 years old with primarily inattentive or combined-type ADHD, who have a demonstrated attention issue. Patients who engage with EndeavorRx demonstrate improvements in a digitally assessed measure, Test of Variables of Attention (TOVA®), of sustained and selective attention and may not display benefits in typical behavioral symptoms, such as hyperactivity. EndeavorRx should be considered for use as part of a therapeutic program that may include clinician-directed therapy, medication, and/or educational programs, which further address symptoms of the disorder.
Of 538 participants using EndeavorRx, 50 participants (9.3%) experienced treatment-related adverse events (probable, likely), and three participants experienced treatment-related adverse events with the digital control, in studies where a control was used. EndeavorRx associated adverse events included frustration (6.1%), headache (1.3%), dizziness (0.6%), emotional reaction (0.4%), nausea (0.4%), and aggression (0.2%). There were no serious adverse events. All adverse events were generally transient. Only 3 events led to device discontinuation, and no subject reported lasting or irreversible effects after discontinuation.
Rx only: Federal law restricts this device to sale by or on the order of a physician. EndeavorRx should only be used by the patient for whom the prescription was written. For medical questions, please contact your child’s healthcare provider. If you are experiencing a medical emergency, please dial 911. EndeavorRx is not intended to be used as a stand-alone therapeutic and is not a substitution for your child’s medication.
If your child experiences frustration, emotional reaction, dizziness, nausea, headache, eye-strain, or joint pain while playing EndeavorRx pause the treatment. If the problem persists contact your child’s healthcare provider. If your child experiences a seizure stop the treatment and contact your child’s healthcare provider.
EndeavorRx may not be appropriate for patients with photo-sensitive epilepsy, color blindness, or physical limitations that restrict use of a mobile device; parents should consult with their child’s healthcare provider.
Please follow all of your mobile device manufacturer’s instructions for the safe operation of your mobile device. For example, this may include appropriate volume settings, proper battery charging, not operating the device if damaged, and proper device disposal. Contact your mobile device manufacturer for any questions or concerns that pertain to your device.